Point-of-care testing for sepsis in remote Australia and for First Nations peoples (2024)

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In Australia, over 55,000 people are diagnosed with sepsis every year1. More than one-quarter of sepsis cases result in death and almost half of all survivors are left with a disability or impaired function2. Populations most at risk of sepsis mortality in Australia are the young, the old, and First Nations peoples (Aboriginal and/or Torres Strait Islander peoples)2. The disparity in excess sepsis risk is most evident in rural and remote locations and in northern Australia.

The disproportionate risk of sepsis for First Nations peoples, like other health inequities, is linked to challenges associated with accessing healthcare services and the negative effects of colonization, including socioeconomic inequity and the lack of access to culturally safe and appropriate healthcare1,3,4. The resultant increased burden of communicable and non-communicable diseases experienced by First Nations peoples, combined with high rates of multimorbidity, can disguise the signs of sepsis. Recognition and treatment of sepsis are therefore often delayed, placing individuals at increased risk of sepsis-related death and disability1. Shifting deficit narratives away from health inequities requires consideration of structural drivers of health outcomes, including accessible healthcare appropriate to community needs. First Nations peoples therefore need appropriate healthcare tools to assist in the detection of life-threatening illnesses such as sepsis within their remote communities.

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Point-of-care testing for sepsis in remote Australia and for First Nations peoples (1)

References

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    Sepsis and Septic Shock - Critical Care Medicine - MSD Manual Professional EditionEarly sepsis recognition: how difficult can this be?Frequently Asked Questions (FAQ) regarding Sepsis

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Acknowledgements

We acknowledge the traditional lands in which this article was created and shaped (Arrernte, Kaurna, Larrakia, Wadawurrung and Eora Nations) and pay respect to their Elders, past, present and emerging.

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Authors and Affiliations

  1. Flinders University, College of Medicine and Public Health, Flinders Health and Medical Research Institute, International Centre for Point-of-Care Testing, Adelaide, South Australia, Australia

    Brooke Spaeth,Mark Shephard&Emma de Courcy-Ireland

  2. Flinders University, College of Medicine and Public Health, Flinders Health and Medical Research Institute, Adelaide, South Australia, Australia

    Brooke Spaeth,Mark Shephard,Richard L. Reed,Jonathan Karnon,Billie Bonevski,Shahid Ullah,Jacqueline H. Stephens,Annabelle Wilson&Emma de Courcy-Ireland

  3. Northern Territory Government, Department of Health, Darwin, Northern Territory, Australia

    Sean Taylor&Rodney Omond

  4. Menzies School of Health Research, Charles Darwin University, Darwin, Northern Territory, Australia

    Sean Taylor&Tina Noutsos

  5. Flinders University, College of Medicine and Public Health, Flinders Health and Medical Research Institute, Darwin, Northern Territory, Australia

    Chris Rissel,Tina Noutsos&James A. Smith

  6. Department of Haematology, Royal Darwin Hospital, Darwin, Northern Territory, Australia

    Tina Noutsos

  7. The George Institute for Global Health, University of New South Wales, Sydney, New South Wales, Australia

    Brett Abbenbroek&Simon Finfer

  8. Faculty of Medicine and Health Sciences, Imperial College London, London, England

    Simon Finfer

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  1. Brooke Spaeth

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Correspondence to Brooke Spaeth.

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The authors declare no competing interests.

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Point-of-care testing for sepsis in remote Australia and for First Nations peoples (2)

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Spaeth, B., Taylor, S., Shephard, M. et al. Point-of-care testing for sepsis in remote Australia and for First Nations peoples. Nat Med (2024). https://doi.org/10.1038/s41591-024-03034-2

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  • DOI: https://doi.org/10.1038/s41591-024-03034-2

Point-of-care testing for sepsis in remote Australia and for First Nations peoples (2024)

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