Clinical Trials Update
October23/30, 2018
JAMA. 2018;320(16):1631. doi:10.1001/jama.2018.16202
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The cannabinoid delta-9 tetrahydrocannabinol (THC) significantly reduced pain in men with chronic radicular neuropathic pain, found a small study in Neurology.
The study included 15 men with medium to high radicular nerve pain for more than 6 months. Before the intervention, participants rated their pain and underwent functional magnetic resonance imaging (fMRI). Nine participants received a single sublingual dose of THC oil and 6 received placebo. Participants assessed their pain 1 hour later and repeated the fMRI 2 hours after the intervention. The groups crossed over at least 1 week after the intervention.
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Slomski A. THC for Chronic Pain. JAMA. 2018;320(16):1631. doi:10.1001/jama.2018.16202
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