Related Papers
Journal of Surgery
Surgery without sufficient indications: an update from Russia
2022 •
Sergei Jargin
This review is an update and continuation of preceding papers on invasive procedures applied in Russia with questionable clinical indications. Certain methods have been applied according to instructions by healthcare authorities and publication of leading specialists, facilitated by lacking professional autonomy. Examples are discussed here and in preceding papers: the overuse of Halsted and Patey mastectomy, preventive electrocoagulation of cervical ectropions without cytotological examination, gastrectomy for peptic ulcers, thoracic and abdominal surgery for bronchial asthma and diabetes mellitus, overuse of surgery in tuberculosis and other pulmonary conditions, overuse of bronchoscopy e.g. in conscripts with supposed pneumonia. Among mechanisms contributing to the persistence of suboptimal methods has been the autocratic or military managerial style discouraging criticism and polemics. Other attributes of this style are the paternalistic approach to patients and insufficient adherence to the principle of informed consent. Some invasive procedures with questionable indications were advocated by first generation military surgeons. Personnel training could have been one of the motives. Note that military and medical ethics are not the same. The comparatively short life expectancy in Russia is a strategic advantage as it necessitates less healthcare investments and tensions. Actually, Russia needs foreign help in the matter of healthcare. In view of the current international tensions, the cooperation has been partly interrupted. Obstacles to the import of medical products have adverse consequences. Under these circ*mstances, the purpose of this article was to remind that, performing a surgical or another invasive procedure, the risk-to-benefit ratio must be kept as low as possible. Insufficient coordination of medical studies and partial isolation from the international scientific community can result in parallelism in research, unnecessary experimentation, and application of invasive methods without sufficient indications.
Journal of Surgery
On the Endoscopic Methods Used with Questionable Indications
Sergei Jargin
Preprints.org
Surgical procedures with questionable indications used in Russia
2024 •
Sergei Jargin
This review summarizes available data on invasive procedures applied with questionable indications in Russia in the recent past: mastectomy with the removal of muscles, gastrectomy for peptic ulcers, splenorenal anastomosis for diabetes mellitus, thoracic surgery for bronchial asthma, overuse of surgery in tuberculosis, excessive and compulsory treatments of alcohol-dependent patients, etc. Among factors contributing to the use of invasive procedures with unproven efficiency have been the partial isolation from international scientific community, insufficient consideration of the principles of professional autonomy, informed consent and scientific polemics, training of medical personnel. It is known that invasive procedures can exert a placebo effect, which might have contributed to reported efficiency of some methods discussed here. However, by definition, placebo must be free of risks.
International Journal of Business and Management (IJBM)
The War in Ukraine: Social and Medical Perspective
2023 •
Sergei Jargin
The full text can be downloaded here and is available at: https://iessociety.org/index.php/Ijbm/index The preprint in Russian: https://www.researchgate.net/publication/369754025_Vojna_na_Ukraine_socialnye_i_psihologiceskie_aspekty_The_Conflict_around_Ukraine_an_Update_in_Russian
Annals of medicine and surgery (2012)
Invasive procedures with questionable indications
2014 •
Sergei Jargin
Insufficient coordination of medical research and partial isolation from the international scientific community can result in application of invasive methods without sufficient indications. Here is presented an overview of renal and pancreatic biopsy studies performed in the course of the operations of pancreatic blood shunting into the systemic blood flow in type 1 diabetic patients. Furthermore a surgical procedure of lung denervation as a treatment method of asthma as well as the use of bronchoscopy for research in asthmatics are discussed here. Today, the upturn in Russian economy enables acquisition of modern equipment; and medical research is on the increase. Under these circ*mstances, the purpose of this letter was to remind that, performing surgical or other invasive procedures, the risk-to-benefit ratio should be kept as low as possible.
Advances in Medicine and Biology
Invasive procedures with unproven efficiency (Part 2): Surgical treatment of tuberculosis
2021 •
Sergei Jargin
The book is available at: https://novapublishers.com/shop/advances-in-medicine-and-biology-volume-191/ PART 1: https://www.researchgate.net/publication/359352070_Chapter_3_Invasive_procedures_with_unproven_efficiency RELATED ARTICLES: https://www.researchgate.net/publication/303304425_Surgical_procedures_with_questionable_indications https://www.researchgate.net/publication/321245511_Invasive_procedures_with_questionable_indications_Prevention_of_a_negligent_custom https://www.researchgate.net/publication/305709637_On_the_endoscopic_methods_used_with_questionable_indications RUSSIAN: https://www.researchgate.net/publication/320727809_Invazivnye_procedury_bez_dostatocnyh_pokazanij_istoria_voprosa https://www.researchgate.net/publication/319547736_O_naucnom_ispolzovanii_biopsii_pocek_Use_of_renal_biopsies_for_research
OSF Preprints
Book Review. Misconduct in Medical Research and Practice. Nova Science Publishers, 2020
2023 •
Sergei Jargin
The preprint is available at: https://osf.io/preprints/osf/zp742 This is the author’s review of the book: Misconduct in medical research and practice. Series: Ethical Issues in the 21st Century. New York: Nova Science Publishers; 2020. doi: 10.52305/GIEZ3244; available at: https://novapublishers.com/shop/misconduct-in-medical-research-and-practice/
Annals of Medicine and Surgery
On the endoscopic methods used in pediatrics with questionable indications
Sergei Jargin
Journal of Addiction & Prevention
Magnesium Supplementation with Special Reference to the Treatment of Alcoholism
2022 •
Sergei Jargin
Supplementation of various substances is sometimes recommended without sufficient indications. To decide whether a supplementation is needed, the question should be answered whether there is a deficiency, and if there is, whether it can be compensated by diet. Magnesium (Mg) deficiency has been associated with cardiovascular diseases, hypertension, stroke, certain neuropsychiatric and metabolic conditions. Hypomagnesemia is above-average in alcoholism; however, alcoholics should not be a priori assumed to have Mg deficiency. Mild depletion does not necessarily require specific therapy. Wherever possible, the oral route of supplementation is preferable. The parenteral route is mandatory in severe Mg deficiency. Hypermagnesemia may result from excessive supplementation. Intravenous infusions of Mg-containing solutions and some other invasive procedures have been used in the former Soviet Union without sufficient indications. The infusion therapy has been recommended also in moderately severe alcohol withdrawal syndrome. In conditions of suboptimal procedural quality assurance, endovascular and other invasive manipulations can lead to the transmission of viral hepatitis, which occurred to treated alcoholic patients. A combination of viral and alcoholic liver injury is unfavorable. It has been suggested to include Mg in routine blood ionograms. Mg contents in different foodstuffs should be taken into account in patients at risk of deficiency for better adjustment of diets.
Journal of Economic and Business Studies
Selected aspects of alcohol consumption and treatment of alcoholics in Russia
2024 •
Sergei Jargin
The article is available at: https://www.pubtexto.com/journals/journal-of-economic-and-business-studies/abstracts/selected-aspects-of-alcohol-consumption-and-treatment-of-alcoholics-in-russia Updated preprint: https://www.researchgate.net/publication/379540132_Alcohol_and_Alcoholism_in_Russia_An_Update